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                          November 2, 2023

       Stephen Gunstream
       President and Chief Executive Officer
       Alpha Teknova, Inc.
       2451 Bert Dr.
       Hollister, CA 95023

                                                        Re: Alpha Teknova, Inc.
                                                            Registration
Statement on Form S-1
                                                            Filed October 25,
2023
                                                            File No. 333-275168

       Dear Stephen Gunstream:

              This is to advise you that we have not reviewed and will not
review your registration
       statement.

               Please refer to Rules 460 and 461 regarding requests for
acceleration. We remind you
       that the company and its management are responsible for the accuracy and
adequacy of their
       disclosures, notwithstanding any review, comments, action or absence of
action by the staff.

                                                        Please contact Cindy
Polynice at 202-551-8707 with any questions.




                          Sincerely,


                          Division of Corporation Finance

                          Office of Life Sciences
       cc:                                              Elizabeth Razzano, Esq.